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The Candida albicans KRE9 gene is required for cell wall β-1,6-glucan synthesis and is essential for growth on glucose

We have isolated CaKRE9, a gene from Candida albicans, that is a functional homologue of the Saccharomyces cerevisiae KRE9 gene involved in β-1,6-glucan synthesis. Disruption of the CaKRE9 gene in C. albicans shows that CaKre9p is required for the synthesis or assembly of this fungal polymer. Homozy...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lussier, Marc, Sdicu, Anne-Marie, Shahinian, Serge, Bussey, Howard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.9825
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