IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells

Lack of the IL-1 receptor accessory protein (IL-1RAcP) abrogates responses to IL-33 and IL-1 in the mouse thymoma clone EL-4 D6/76 cells. Reconstitution with full-length IL-1RAcP is sufficient to restore responsiveness to IL-33 and IL-1. IL-33 activates IL-1 receptor-associated kinase-1, cJun-N-term...

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Detalhes bibliográficos
Main Authors: Ali, Shafaqat, Huber, Michael, Kollewe, Christian, Bischoff, Stephan C., Falk, Werner, Martin, Michael U.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141833/
https://ncbi.nlm.nih.gov/pubmed/18003919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705939104
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