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CD36 Mediates the In Vitro Inhibitory Effects of Thrombospondin-1 on Endothelial Cells

Thrombospondin-1 (TSP-1) is a naturally occurring inhibitor of angiogenesis that is able to make normal endothelial cells unresponsive to a wide variety of inducers. Here we use both native TSP-1 and small antiangiogenic peptides derived from it to show that this inhibition is mediated by CD36, a tr...

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Autors principals: Dawson, David W., Pearce, S. Frieda A., Zhong, Ruiqin, Silverstein, Roy L., Frazier, William A., Bouck, Noël P.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141641/
https://ncbi.nlm.nih.gov/pubmed/9245797
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