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Dictyostelium RasG Is Required for Normal Motility and Cytokinesis, But Not Growth

RasG is the most abundant Ras protein in growing Dictyostelium cells and the closest relative of mammalian Ras proteins. We have generated null mutants in which expression of RasG is completely abolished. Unexpectedly, RasG (−) cells are able to grow at nearly wild-type rates. However, they exhibit...

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Detalhes bibliográficos
Main Authors: Tuxworth, Richard I., Cheetham, Janet L., Machesky, Laura M., Spiegelmann, George B., Weeks, Gerald, Insall, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141629/
https://ncbi.nlm.nih.gov/pubmed/9245789
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