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Use of the CD107 mobilization assay reveals that cytotoxic T lymphocytes with novel MHC-Ib restriction are activated during Listeria monocytogenes infection

Detection of cytotoxic activity by pathogen-specific T cells of unknown antigenic specificity is difficult due to the limitations of using infected cells, instead of peptide-pulsed cells, as targets. We report here that the recently described CD107 mobilization assay readily allowed for the ex vivo...

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Autori principali: McElroy, Denise S., Badstibner, Adina M., D’Orazio, Sarah E.F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140280/
https://ncbi.nlm.nih.gov/pubmed/17900608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.08.005
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