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HIV-1 integrates into resting CD4(+) T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration

Human Immunodeficiency Virus Type I (HIV-1) establishes a latent reservoir early in infection that is resistant to the host immune response and treatment with highly active antiretroviral therapy (HAART). The best understood of these reservoirs forms in resting CD4(+) T cells. While it remains uncle...

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Détails bibliographiques
Auteurs principaux: Agosto, Luis M., Yu, Jianqing J., Dai, Jihong, Kaletsky, Rachel, Monie, Daphne, O'Doherty, Una
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140271/
https://ncbi.nlm.nih.gov/pubmed/17631931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.06.001
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