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Procathepsin D secreted by HaCaT keratinocyte cells – a novel regulator of keratinocyte growth

Procathepsin D (pCD), the precursor form of lysosomal aspartic protease, is overexpressed and secreted by various carcinomas. The fact that secreted pCD plays an essential role in progression of cancer has been established. In this study, we describe substantial secretion of pCD by the human keratin...

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Main Authors: Vashishta, Aruna, Ohri, Sujata Saraswat, Vetvickova, Jana, Fusek, Martin, Ulrichova, Jitka, Vetvicka, Vaclav
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140195/
https://ncbi.nlm.nih.gov/pubmed/17532541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2007.03.008
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