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An acetylation/deacetylation cycle controls the export of sterols and steroids from S. cerevisiae

Sterol homeostasis in eukaryotic cells relies on the reciprocal interconversion of free sterols and steryl esters. Here we report the identification of a novel reversible sterol modification in yeast, the sterol acetylation/deacetylation cycle. Sterol acetylation requires the acetyltransferase ATF2,...

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Detalhes bibliográficos
Main Authors: Tiwari, Rashi, Köffel, René, Schneiter, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140111/
https://ncbi.nlm.nih.gov/pubmed/18034159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601924
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