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In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans

In the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) play important roles as intermediates. Primary siRNAs are produced from trigger dsRNAs by an RNaseIII-related enzyme called Dicer; in some organisms, secondary siRNAs are also produced by processes involving RNA-dependent RNA po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aoki, Kazuma, Moriguchi, Hiromi, Yoshioka, Tomoko, Okawa, Katsuya, Tabara, Hiroaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140100/
https://ncbi.nlm.nih.gov/pubmed/18007599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601910
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