Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents

Ultraviolet B and genotoxic drugs induce the expression of a vascular endothelial growth factor A (VEGF-A) splice variant (VEGF111) encoded by exons 1–4 and 8 in many cultured cells. Although not detected in a series of normal human and mouse tissue, VEGF111 expression is induced in MCF-7 xenografts...

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Main Authors: Mineur, Pierre, Colige, Alain C., Deroanne, Christophe. F., Dubail, Johanne, Kesteloot, Frédéric, Habraken, Yvette, Noël, Agnès, Vöö, Stefan, Waltenberger, Johannes, Lapière, Charles M., Nusgens, Betty V., Lambert, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140032/
https://ncbi.nlm.nih.gov/pubmed/18086921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703052
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