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Differential Sorting of Lysosomal Enzymes Out of the Regulated Secretory Pathway in Pancreatic β-Cells

In cells specialized for secretory granule exocytosis, lysosomal hydrolases may enter the regulated secretory pathway. Using mouse pancreatic islets and the INS-1 β-cell line as models, we have compared the itineraries of procathepsins L and B, two closely related members of the papain superfamily k...

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Bibliographische Detailangaben
Hauptverfasser: Kuliawat, Regina, Klumperman, Judith, Ludwig, Thomas, Arvan, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139876/
https://ncbi.nlm.nih.gov/pubmed/9151667
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