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Dissociation of Coatomer from Membranes Is Required for Brefeldin A–induced Transfer of Golgi Enzymes to the Endoplasmic Reticulum

Addition of brefeldin A (BFA) to mammalian cells rapidly results in the removal of coatomer from membranes and subsequent delivery of Golgi enzymes to the endoplasmic reticulum (ER). Microinjected anti-EAGE (intact IgG or Fab-fragments), antibodies against the “EAGE”-peptide of β-COP, inhibit BFA-in...

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Bibliographische Detailangaben
Hauptverfasser: Scheel, Jochen, Pepperkok, Rainer, Lowe, Martin, Griffiths, Gareth, Kreis, Thomas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139784/
https://ncbi.nlm.nih.gov/pubmed/9128245
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