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ANTIBODY RESPONSES TO ANTIGENIC DETERMINANTS OF INFLUENZA VIRUS HEMAGGLUTININ : II. Original Antigenic Sin: A Bone Marrow-Derived Lymphocyte Memory Phenomenon Modulated by Thymus-Derived Lymphocytes

Mice immunized sequentially with two related influenza virus hemagglutinins (HA) produced a secondary antibody response with two different specificities. Some antibodies were specific for determinants common to both HA's. Paradoxically, some antibodies were directed to determinants existing onl...

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Detalles Bibliográficos
Main Authors: Virelizier, Jean-Louis, Allison, Anthony C., Schild, Geoffrey C.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1974
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139742/
https://ncbi.nlm.nih.gov/pubmed/4139234
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