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A NEUTROPHIL-DEPENDENT PATHWAY FOR THE GENERATION OF A NEUTRAL PEPTIDE MEDIATOR : PARTIAL CHARACTERIZATION OF COMPONENTS AND CONTROL BYα-1-ANTITRYPSIN

A biologically active neutral peptide mediator is cleaved from a plasma protein substrate by an α-1-antitrypsin-inhibitable serine protease apparently residing on the membrane of the human neutrophil. The peptide mediator has an approximate mol wt of 1,000, and is distinguished from the kinin peptid...

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Bibliographic Details
Main Authors: Wintroub, Bruce U., Goetzl, Edward J., Austen, K. Frank
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139623/
https://ncbi.nlm.nih.gov/pubmed/4547125
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