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DIRECT EVIDENCE FOR HAGEMAN FACTOR (FACTOR XII) ACTIVATION BY BACTERIAL LIPOPOLYSACCHARIDES (ENDOTOXINS)

Purified precursor Hageman factor has been demonstrated to bind to soluble bacterial lipopolysaccharide (LPS, endotoxin) isolated from Escherichia coli 0111:B4, and this complex has been shown to have the capacity to convert prekallikrein to its active form. In addition, LPS-activated Hageman factor...

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Detalles Bibliográficos
Main Authors: Morrison, David C., Cochrane, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1974
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139619/
https://ncbi.nlm.nih.gov/pubmed/4378413
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