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GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : I. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN CELLS IN MIXED LEUKOCYTE CULTURES

Mouse cytotoxic T lymphocytes (CTL) were generated in mixed leukocyte cultures (MLC) using spleen cells as responding cells and irradiated allogeneic spleen cells as stimulating cells. Cytotoxicity was assessed by a quantitative (51)Cr assay system and the relative frequency of CTL in individual cel...

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Detalles Bibliográficos
Main Authors: Cerottini, Jean-Charles, Engers, Howard D., MacDonald, H. Robson, Brunner, K. Theodor
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1974
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139609/
https://ncbi.nlm.nih.gov/pubmed/4278108
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