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THE MODULATING INFLUENCE OF CYCLIC NUCLEOTIDES UPON LYMPHOCYTE-MEDIATED CYTOTOXICITY

The capacity of allosensitized thymus-derived lymphocytes to destroy target cells bearing donor alloantigens is modulated by the cellular levels of cyclic AMP and cyclic GMP. Increases in the cyclic AMP levels of attacking lymphocytes by stimulation with prostaglandin E(1), isoproterenol, and choler...

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Main Authors: Strom, Terry B., Carpenter, Charles B., Garovoy, Marvin R., Austen, K. Frank, Merrill, John P., Kaliner, Michael
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1973
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139402/
https://ncbi.nlm.nih.gov/pubmed/4352584
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