ACTIVE SUPPRESSION OF IMMUNOGLOBULIN ALLOTYPE SYNTHESIS : III. IDENTITICATION OF T CELLS AS RESPONSIBLE FOR SUPPRESSION BY CELLS FROM SPLEEN, THYMUS, LYMPH NODE, AND BONE MARROW

Thymus-derived cells (T cells) that actively suppress production of IgG2a immunoglobulins carrying the Ig-1b allotype have been found in adult (SJL x BALB/c)F(1) mice exposed to anti-Ig-1b early in life. The suppression is specific for Ig-1b. The allelic product, Ig-1a, is unaffected. Spleen, lymph...

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Main Authors: Herzenberg, Leonore A., Chan, Eva L., Ravitch, Myrnice M., Riblet, Roy J., Herzenberg, Leonard A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1973
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139347/
https://ncbi.nlm.nih.gov/pubmed/4541122
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