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TOXIC EFFECTS OF STREPTOCOCCAL M PROTEIN ON PLATELETS AND POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BLOOD

Purified M protein isolated from Group A streptococci produced cytotoxic reactions in normal human blood in vitro. In the presence of M antigen, platelets aggregated, fused, and lysed. Polymorphonuclear leukocytes (PMN) surrounded the platelet aggregates, then became highly vacuolated and lysed. In...

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Autori principali: Beachey, Edwin H., Stollerman, Gene H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1971
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139042/
https://ncbi.nlm.nih.gov/pubmed/4934500
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