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IMMUNE RESPONSE TO CHEMICALLY MODIFIED FLAGELLIN : I. INDUCTION OF ANTIBODY TOLERANCE TO FLAGELLIN BY ACETOACETYLATED DERIVATIVES OF THE PROTEIN
Flagellin (mol. wt. 40,000) from S. adelaide organisms was acetoacetylated to varying extents with diketene (acetoacetic anhydride). Chemical studies demonstrated that the amino groups of flagellin were more readily acetoacetylated than the hydroxyl groups. Several antigenic tests revealed that as f...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2139033/ https://ncbi.nlm.nih.gov/pubmed/4997585 |
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