CARRIER FUNCTION IN ANTI-HAPTEN ANTIBODY RESPONSES : IV. EXPERIMENTAL CONDITIONS FOR THE INDUCTION OF HAPTEN-SPECIFIC TOLERANCE OR FOR THE STIMULATION OF ANTI-HAPTEN ANAMNESTIC RESPONSES BY "NONIMMUNOGENIC" HAPTEN-POLYPEPTIDE CONJUGATES

Administration of nonimmunogenic 2,4-dinitrophenyl (DNP) conjugates of copolymers of D or L-glutamic acid and lysine (GL) induces hapten-specific tolerance in nonimmune and DNP-ovalbumin-primed strain 13 guinea pigs. This tolerant state is evidenced by depressed anti-DNP antibody synthesis in respon...

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Main Authors: Katz, David H., Davie, Joseph M., Paul, William E., Benacerraf, Baruj
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1971
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139028/
https://ncbi.nlm.nih.gov/pubmed/4397662
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