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MACROPHAGE-MELANOMA CELL HETEROKARYONS : III. THE ACTIVATION OF MACROPHAGE DNA SYNTHESIS. STUDIES WITH INHIBITORS OF PROTEIN SYNTHESIS AND WITH SYNCHRONIZED MELANOMA CELLS

Dormant macrophage nuclei initiate DNA synthesis 2–3 hr after fusion of macrophages with exponentially growing melanoma cells. Cycloheximide treatment (1–5 µg/ml) of heterokaryons during the preceding lag period inhibits the initiation of macrophage DNA synthesis, in a reversible fashion. Each type...

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Detalles Bibliográficos
Main Authors: Gordon, Saimon, Cohn, Zanvil
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1971
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138993/
https://ncbi.nlm.nih.gov/pubmed/4106491
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