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SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : I. ADAPTATION OF THE MERWIN PLASMA CELL TUMOR-11 TO CULTURE, CLONING, AND CHARACTERIZATION OF GAMMA GLOBULIN SUBUNITS
MPC-11 myeloma tumor cells were adapted to growth in continuous culture. The cultured cells resembled the parent tumor in that they produced the fully assembled gamma globulin molecules as well as six unassembled molecules. Although cultured and tumor cells synthesized excess light chains, the molar...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1970
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2138817/ https://ncbi.nlm.nih.gov/pubmed/4189836 |
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