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SPECIFICITY OF CELLULAR IMMUNE RESPONSES : ANTIGEN CONCENTRATION DEPENDENCE OF STIMULATION OF DNA SYNTHESIS IN VITRO BY SPECIFICALLY SENSITIZED CELLS, AS AN EXPRESSION OF THE BINDING CHARACTERISTICS OF CELLULAR ANTIBODY

In vitro antigen stimulation of DNA synthesis in lymph node cultures from immunized guinea pigs can be obtained with very low (10(–4) µg/ml) antigen concentrations in the culture fluid. Immunization with low doses of DNP-GPA leads to a cell population capable of being stimulated, on the average, by...

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Detalhes bibliográficos
Main Authors: Paul, William E., Siskind, Gregory W., Benacerraf, Baruj
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138435/
https://ncbi.nlm.nih.gov/pubmed/4864671
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