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HAPTEN CARRIER RELATIONSHIPS IN THE DNP-PLL·FOREIGN ALBUMIN COMPLEX SYSTEM: INDUCTION OF TOLERANCE AND STIMULATION OF CELLS IN VITRO

Genetic nonresponder guinea pigs made tolerant to BSA and then immunized with DNP-PLL·BSA failed to make anti-DNP-PLL antibodies. Thus, tolerance to a carrier protein renders animals unresponsive to the hapten which it bears. The addition in vitro of DNP-PLL or DNP-GL to lymph node cell cultures der...

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Autors principals: Green, Ira, Paul, William E., Benacerraf, Baruj
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1968
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138427/
https://ncbi.nlm.nih.gov/pubmed/4965466
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