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BIOLOGICAL ACTIVITY OF THE CLEAVAGE PRODUCT OF HUMAN IMMUNOGLOBULIN G WITH CYANOGEN BROMIDE

Treatment of human IgG with cyanogen bromide in 0.05 M HCl under specified conditions resulted in the cleavage of about half of its methionyl peptide bonds. A major fragment of about 5S was isolated from the reaction mixture by gel filtration in quantitative yield. The CNBr fragment reacted fully wi...

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Detalhes bibliográficos
Main Authors: Lahav, Mira, Arnon, Ruth, Sela, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1967
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138212/
https://ncbi.nlm.nih.gov/pubmed/4164692
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