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Regulation of Actin Polymerization in Cell-free Systems by GTPγS and Cdc42

We have established a cell-free system to investigate pathways that regulate actin polymerization. Addition of GTPγS to lysates of polymorphonuclear leukocytes (PMNs) or Dictyostelium discoideum amoeba induced formation of filamentous actin. The GTPγS appeared to act via a small G-protein, since it...

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Detalles Bibliográficos
Main Authors: Zigmond, Sally H., Joyce, Michael, Borleis, Jane, Bokoch, Gary M., Devreotes, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138194/
https://ncbi.nlm.nih.gov/pubmed/9230078
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