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IL-31–IL-31R interactions negatively regulate type 2 inflammation in the lung

Interleukin (IL) 31Rα (glycoprotein 130–like monocyte receptor and glycoprotein 130–like receptor) heterodimerizes with oncostatin M receptor β to bind IL-31, a cytokine expressed preferentially by CD4(+) T helper type 2 (Th2) cells. However, the functions of IL-31–IL-31R signaling in immune regulat...

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Dettagli Bibliografici
Autori principali: Perrigoue, Jacqueline G., Li, Ji, Zaph, Colby, Goldschmidt, Michael, Scott, Phillip, de Sauvage, Frederic J., Pearce, Edward J., Ghilardi, Nico, Artis, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137900/
https://ncbi.nlm.nih.gov/pubmed/17353366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061791
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