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PRODUCTION OF INFLAMMATORY CHANGES IN THE MICROCIRCULATION BY CATIONIC PROTEINS EXTRACTED FROM LYSOSOMES

Lysosomal granules of rabbit exudate polymorphonuclear (PMN) leucocytes were isolated and then lysed by freezing-thawing. Topical application of this material to rat and rabbit mesentery produced sticking and emigration of leucocytes, stasis of blood flow, and petechial hemorrhage. The granule-free,...

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Autors principals: Janoff, Aaron, Zweifach, Benjamin W.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1964
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137856/
https://ncbi.nlm.nih.gov/pubmed/14247717
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