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STUDIES ON THE PATHOGENESIS OF FEVER : X. THE EFFECT OF CERTAIN ENZYME INHIBITORS ON THE PRODUCTION AND ACTIVITY OF LEUCOCYTIC PYROGEN
The production of endogenous pyrogen by intact granulocytes obtained from acute peritoneal exudates is blocked by arsenite, iodoacetate, p-chloromercuribenzoate, and N-ethylmaleimide in concentrations of 2 x 10(–4) M. When the concentration of these sulfhydryl-reactive enzyme inhibitors is increased...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1962
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2137481/ https://ncbi.nlm.nih.gov/pubmed/14453158 |
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