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SYNTHESIS OF VIRUS-SPECIFIC POLYMERS IN ADENOVIRUS-INFECTED CELLS: EFFECT OF 5-FLUORODEOXYURIDINE

Biochemical synthesis in adenovirus-infected HeLa cells was studied utilizing 5-fluorodeoxyuridine (5-FUDR), a potent inhibitor of deoxyribonucleic acid production. Synthesis of saline-soluble DNA and infectious virus was completely suppressed by addition of the analogue to cells as late as 10 hours...

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Detalhes bibliográficos
Main Authors: Flanagan, John F., Ginsberg, Harold S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1962
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137384/
https://ncbi.nlm.nih.gov/pubmed/13893423
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