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RELATIONSHIP BETWEEN STRUCTURE OF BENZIMIDAZOLE DERIVATIVES AND SELECTIVE VIRUS INHIBITORY ACTIVITY : INHIBITION OF POLIOVIRUS MULTIPLICATION AND CYTOPATHIC EFFECTS BY 2-(α-HYDROXYBENZYL)-BENZIMIDAZOLE, AND ITS 5-CHLORO DERIVATIVE

The virus inhibitory activity and selectivity of certain benzimidazole, benzotriazole, and naphthimidazole derivatives were determined with influenza B and polio type 2 viruses. Among the sixty-five compounds examined, several were highly active inhibitors of influenza B virus multiplication in the...

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Main Authors: Tamm, Igor, Bablanian, Rostom, Nemes, Marjorie M., Shunk, Clifford H., Robinson, Franklin M., Folkers, Karl
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1961
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137381/
https://ncbi.nlm.nih.gov/pubmed/13775109
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