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Drug-free induction of a chloramphenicol acetyltransferase gene in Bacillus subtilis by stalling ribosomes in a regulatory leader.

The plasmid gene cat-86 is induced by chloramphenicol in Bacillus subtilis, resulting in the synthesis of the gene product chloramphenicol acetyltransferase. Induction is due to a posttranscriptional regulatory mechanism in which the inducer, chloramphenicol, activates translation of cat-86 mRNA. We...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Duvall, E J, Ambulos, N P, Lovett, P S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3114238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.9.4235-4241.1987
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