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Lumican Regulates Collagen Fibril Assembly: Skin Fragility and Corneal Opacity in the Absence of Lumican

Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. Mice homozygous for a null mutation in lumican display skin laxity and fragility resembling certain types of Ehlers-Danlos syndrome. In additio...

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Bibliografische gegevens
Hoofdauteurs: Chakravarti, Shukti, Magnuson, Terry, Lass, Jonathan H., Jepsen, Karl J., LaMantia, Christian, Carroll, Heidi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137175/
https://ncbi.nlm.nih.gov/pubmed/9606218
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