Interleukin 10 secretion in relation to human IL-10 locus haplotypes

Stimulation of human blood cultures with bacterial lipopolysaccharide (LPS) shows large inter-individual variation in interleukin 10 (IL-10) secretion, which has been shown to have a genetic component of over 70%. Alleles at two microsatellite loci in the 4 kb immediately upstream of the human IL-10...

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Autors principals: Eskdale, Joyce, Gallagher, Grant, Verweij, Cor L., Keijsers, Vivian, Westendorp, Rudi G. J., Huizinga, Tom W. J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21361/
https://ncbi.nlm.nih.gov/pubmed/9689103
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