Methylation-dependent transcription controls plasmid replication of the CloDF13 cop-1(Ts) mutant.

The CloDF13 cop-1(Ts) mutant expresses a temperature-dependent plasmid copy number. At 42 degrees C the mutant shows a "runaway" behavior, and cells harboring this plasmid are killed. The cop-1(Ts) mutation is a G-to-A transition that disturbs one of the two methylation sites which are loc...

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Bibliographic Details
Main Authors: van Putten, A J, de Lang, R, Veltkamp, E, Nijkamp, H J, Van Solingen, P, van den Berg, J A
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC213542/
https://ncbi.nlm.nih.gov/pubmed/2430942
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