Mineralocorticoid receptor knockout mice: Pathophysiology of Na(+) metabolism

Mineralocorticoid receptor (MR)-deficient mice were generated by gene targeting. These animals had a normal prenatal development. During the first week of life, MR-deficient (−/−) mice developed symptoms of pseudohypoaldosteronism. They finally lost weight and eventually died at around day 10 after...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Berger, Stefan, Bleich, Markus, Schmid, Wolfgang, Cole, Timothy J., Peters, Jörg, Watanabe, Haruko, Kriz, Wilhelm, Warth, Richard, Greger, Rainer, Schütz, Günther
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9424
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