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Exploring Transferrin-Receptor Interactions at the Single-Molecule Level

Interaction between the iron transporter protein transferrin (Tf) and its receptor at the cell surface is fundamental for most living organisms. Tf receptor (TfR) binds iron-loaded Tf (holo-Tf) and transports it to endosomes, where acidic pH favors iron release. Iron-free Tf (apo-Tf) is then brought...

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Detalhes bibliográficos
Main Authors: Yersin, Alexandre, Osada, Toshiya, Ikai, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134874/
https://ncbi.nlm.nih.gov/pubmed/17872962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114637
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