Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA

Cytosine-methylation changes are stable and thought to be among the earliest events in tumorigenesis. Theoretically, DNA carrying tumor-specifying methylation patterns escape the tumors and may be found circulating in the sera from cancer patients, thus providing the basis for development of noninva...

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Detalhes bibliográficos
Main Authors: Korshunova, Yulia, Maloney, Rebecca K., Lakey, Nathan, Citek, Robert W., Bacher, Blaire, Budiman, Arief, Ordway, Jared M., McCombie, W. Richard, Leon, Jorge, Jeddeloh, Jeffrey A., McPherson, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134785/
https://ncbi.nlm.nih.gov/pubmed/18032725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6883307
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