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Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs

By integrating genome-wide maps of RNA polymerase II (Polr2a) binding with gene expression data and H3ac and H3K4me3 profiles, we characterized promoters with enriched activity in mouse embryonic stem cells (mES) as well as adult brain, heart, kidney, and liver. We identified ∼24,000 promoters acros...

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Autori principali: Barrera, Leah O., Li, Zirong, Smith, Andrew D., Arden, Karen C., Cavenee, Webster K., Zhang, Michael Q., Green, Roland D., Ren, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134779/
https://ncbi.nlm.nih.gov/pubmed/18042645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6654808
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