Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs

By integrating genome-wide maps of RNA polymerase II (Polr2a) binding with gene expression data and H3ac and H3K4me3 profiles, we characterized promoters with enriched activity in mouse embryonic stem cells (mES) as well as adult brain, heart, kidney, and liver. We identified ∼24,000 promoters acros...

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Autores principales: Barrera, Leah O., Li, Zirong, Smith, Andrew D., Arden, Karen C., Cavenee, Webster K., Zhang, Michael Q., Green, Roland D., Ren, Bing
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Materias:
Letter
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134779/
https://ncbi.nlm.nih.gov/pubmed/18042645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6654808
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