Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster

Mitochondrial dysfunction is associated with many human diseases. There has not been a systematic genetic approach for identifying regulators of basal mitochondrial biogenesis and function in higher eukaryotes. We performed a genome-wide RNA interference (RNAi) screen in Drosophila cells using mitoc...

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Detalhes bibliográficos
Main Authors: Chen, Jian, Shi, Xiaoying, Padmanabhan, Ranjani, Wang, Qiong, Wu, Zhidan, Stevenson, Susan C., Hild, Marc, Garza, Dan, Li, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134776/
https://ncbi.nlm.nih.gov/pubmed/18042644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6940108
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