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Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility

Decorin is a member of the expanding group of widely distributed small leucine-rich proteoglycans that are expected to play important functions in tissue assembly. We report that mice harboring a targeted disruption of the decorin gene are viable but have fragile skin with markedly reduced tensile s...

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Hlavní autoři: Danielson, Keith G., Baribault, Helene, Holmes, David F., Graham, Helen, Kadler, Karl E., Iozzo, Renato V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134287/
https://ncbi.nlm.nih.gov/pubmed/9024701
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