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Production of monoclonal antibodies to hepatitis B surface and core antigens, and use in the detection of viral antigens in liver biopsies.

Hybridomas secreting monoclonal antibodies to HBsAg and HBcAg were prepared from immunized mice. An antibody capture radioimmunoassay was used to detect and select appropriate hybrids for propagation and cloning. The advantages of this assay were discussed. The resulting monoclonal antibodies were c...

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Bibliographic Details
Main Authors: Tedder, R. S., Guarascio, P., Yao, J. L., Lord, R. B., Eddleston, A. L.
Format: Artigo
Language:Inglês
Published: Cambridge University Press 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134181/
https://ncbi.nlm.nih.gov/pubmed/6337208
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