Isolation of the Candida albicans histidinol dehydrogenase (HIS4) gene and characterization of a histidine auxotroph.

Genetic studies were done with Candida albicans CBS 562. Various auxotrophs were isolated following mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. SAG5 (his4C), a stable histidine auxotroph defective in histidinol dehydrogenase activity, was characterized and chosen for further molecular stu...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Altboum, Z, Gottlieb, S, Lebens, G A, Polacheck, I, Segal, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2163392/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.7.3898-3904.1990
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