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Structural and functional characterization of tnpI, a recombinase locus in Tn21 and related beta-lactamase transposons.

A novel discrete mobile DNA element from Tn21 from the plasmid R100.1 is described, and its mobilization function was confirmed experimentally. In addition, the element behaves as a recombinase-active locus (tnpI) which facilitates insertions of antibiotic resistance genes as modules or cassettes at...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Mercier, J, Lachapelle, J, Couture, F, Lafond, M, Vézina, G, Boissinot, M, Levesque, R C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2163386/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.7.3745-3757.1990
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