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Targeted Disruption of the LAMA3 Gene in Mice Reveals Abnormalities in Survival and Late Stage Differentiation of Epithelial Cells

Laminin 5 regulates anchorage and motility of epithelial cells through integrins α6β4 and α3β1, respectively. We used targeted disruption of the LAMA3 gene, which encodes the α3 subunit of laminin 5 and other isoforms, to examine developmental functions that are regulated by adhesion to the basement...

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Detalles Bibliográficos
Main Authors: Ryan, Maureen C., Lee, Keesook, Miyashita, Yuko, Carter, William G.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133157/
https://ncbi.nlm.nih.gov/pubmed/10366601
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