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Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction.

Fusions of lacZ were constructed to genes in each of the loci involved in de novo synthesis of IMP. The expression of each pur-lacZ fusion was determined in isogenic purR and purR+ strains. These measurements indicated 5- to 17-fold coregulation of genes purF, purHD, purC, purMN, purL, and purEK and...

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Bibliographic Details
Main Authors: He, B, Shiau, A, Choi, K Y, Zalkin, H, Smith, J M
Format: Artigo
Language:Inglês
Published: 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC213288/
https://ncbi.nlm.nih.gov/pubmed/2198266
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