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ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT2 transporter regulate glucose-stimulated insulin secretion

As part of our research into the liver-directed gene therapy of Type I diabetes, we have engineered a human hepatoma cell line (HEPG2ins/g cells) to store and secrete insulin to a glucose stimulus. The aim of the present study was to determine whether HEPG2ins/g cells respond to glucose via signalin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Guo Jun, Simpson, Ann M., Swan, M. Anne, Tao, Chang, Tuch, Bernard E., Crawford, Russell M., Jovanovic, Aleksandar, Martin, Donald K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132862/
https://ncbi.nlm.nih.gov/pubmed/12958175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.02-0051fje
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