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Sorting Mechanisms Regulating Membrane Protein Traffic in the Apical Transcytotic Pathway of Polarized MDCK Cells

The transcytotic pathway followed by the polymeric IgA receptor (pIgR) carrying its bound ligand (dIgA) from the basolateral to the apical surface of polarized MDCK cells has been mapped using morphological tracers. At 20°C dIgA-pIgR internalize to interconnected groups of vacuoles and tubules that...

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Detalhes bibliográficos
Main Authors: Gibson, A., Futter, C.E., Maxwell, S., Allchin, E.H., Shipman, M., Kraehenbuhl, J.-P., Domingo, D., Odorizzi, G., Trowbridge, I.S., Hopkins, C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132803/
https://ncbi.nlm.nih.gov/pubmed/9763422
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